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1

Molecular Biology and Pharmacology of PDE-5—Inhibitor Therapy for Erectile Dysfunction

Jackie D. Corbin, Sharron H. Francis

Journal:

Journal of Andrology

Year:

2003

Language:

english

File:

PDF, 80 KB

english, 2003

2

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

Croft, Brittany, Ohnesorg, Thomas, Hewitt, Jacky, Bowles, Josephine, Quinn, Alexander, Tan, Jacqueline, Corbin, Vincent, Pelosi, Emanuele, van den Bergen, Jocelyn, Sreenivasan, Rajini, Knarston, Ingri

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 919 KB

english, 2018

3

Cyclic Nucleotide-Dependent Protein Kinases: Intracellular Receptors for cAMP and cGMP Action

Francis, Sharron H., Corbin, Jackie D.

Journal:

Critical Reviews in Clinical Laboratory Sciences

Year:

1999

Language:

english

File:

PDF, 529 KB

english, 1999

4

Phosphodiesterase-5 Inhibition: the Molecular Biology of Erectile Function and Dysfunction

Francis, Sharron H., Corbin, Jackie D.

Journal:

Urologic Clinics of North America

Year:

2005

Language:

english

File:

PDF, 357 KB

english, 2005

5

Critical Amino Acids in Phosphodiesterase-5 Catalytic Site That Provide for High-Affinity Interaction with Cyclic Guanosine Monophosphate and Inhibitors †

Zoraghi, Roya, Francis, Sharron H., Corbin, Jackie D.

Journal:

Year:

2007

Language:

english

File:

PDF, 381 KB

english, 2007

6

Mechanistic Studies of cAMP-Dependent Protein Kinase Actio

Bramson, Harold Neal, Kaiser, Emil Thomas, Mildvan, Albert S., Corbin, Jackie D.

Journal:

Critical Reviews in Biochemistry and Molecular Biology

Year:

1984

Language:

english

File:

PDF, 1.98 MB

english, 1984

7

Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities

Jackie D. Corbin, Illarion V. Turko, Alfreda Beasley, Sharron H. Francis

Journal:

Year:

2000

Language:

english

File:

PDF, 629 KB

english, 2000

8

Allosteric sites of phosphodiesterase-5 (PDE5) : A potential role in negative feedback regulation of cGMP signaling in corpus cavernosum

Venkatesh K. Gopal, Sharron H. Francis, Jackie D. Corbin

Journal:

Year:

2001

Language:

english

File:

PDF, 689 KB

english, 2001

9

Negative feedback control of the nitric oxide/cGMP pathway in smooth muscle

Jackie Corbin, Emmanuel P Bessay, Mitsi A Blount, Roya Zoraghi, Gary Z Morris, James L Weeks, Hengming Ke, Sharron H Francis

Journal:

BMC Pharmacology

Year:

2007

Language:

english

File:

PDF, 182 KB

english, 2007

10

Characterization of the isolated cAMP-binding B domain of cAMP-dependent protein kinase

John B. Shabb, Mark A. Kapphahn, Wallace M. Muhonen, Celeste E. Poteet, Nancy E. Baker, Jackie D. Corbin

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 1.65 MB

english, 1995

11

Autophosphorylation: a salient feature of protein kinases

Jeffrey A. Smith, Sharron H. Francis, Jackie D. Corbin

Journal:

Molecular and Cellular Biochemistry

Year:

1993

Language:

english

File:

PDF, 2.24 MB

english, 1993

12

A photoaffinity probe covalently modifies the catalytic site of the cGMP-binding cGMP-specific phosphodiesterase (PDE-5)

Jackie D. Corbin, Alfreda Beasley, Illarion V. Turko, Tamara L. Haik, Kimberly A. Mangum, Jack N. Wells, Sharron H. Francis, Konjeti R. Sekhar

Journal:

Cell Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 1.01 MB

english, 1998

13

Molecular mechanisms and pharmacokinetics of phosphodiesterase-5 antagonists

Sharron H. Francis, Jackie D. Corbin

Journal:

Current Urology Reports

Year:

2003

Language:

english

File:

PDF, 504 KB

english, 2003

14

Phosphorylation of Tyr7, Tyr10, and Ser27 of α-Chain in H+,K+-ATPase by Intrinsic and Extrinsic Kinases

KATSUHIKO TOGAWA, SHUNJI KAYA, MASANOBU MORI, AKIRA SHIMADA, TOSHIAKI IMAGAWA, KAZUYA TANIGUCHI, SVEN MÅRDH, JACKIE CORBIN, USHIO KIKKAWA

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 178 KB

english, 1997

15

Dual ion-channel regulation by cyclic GMP and cyclic GMP-dependent protein kinase

Light, Douglas B., Corbin, Jackie D., Stanton, Bruce A.

Journal:

Year:

1990

File:

PDF, 542 KB

1990

16

Cytoskeletal disrupting agents prevent calmodulin kinase, iq domain and voltage-dependent facilitation of l-type ca2+ Channels

Igor Dzhura, Yuejin Wu, Roger J. Colbran, Jackie D. Corbin, Jeffrey R. Balser, Mark E. Anderson

Journal:

The Journal of Physiology

Year:

2002

Language:

english

File:

PDF, 273 KB

english, 2002

17

Two lobes and a cleft

Journal:

Current Biology

Year:

1991

Language:

english

File:

PDF, 327 KB

english, 1991

18

Cyclic GMP specifically suppresses Type-Iα cGMP-dependent protein kinase expression by ubiquitination

Nupur B. Dey, Jennifer L. Busch, Sharron H. Francis, Jackie D. Corbin, Thomas M. Lincoln

Journal:

Cellular Signalling

Year:

2009

Language:

english

File:

PDF, 737 KB

english, 2009

19

Allosteric-site and catalytic-site ligand effects on PDE5 functions are associated with distinct changes in physical form of the enzyme

Jackie D. Corbin, Roya Zoraghi, Sharron H. Francis

Journal:

Cellular Signalling

Year:

2009

Language:

english

File:

PDF, 733 KB

english, 2009

20

Metal ion stimulators of PDE5 cause similar conformational changes in the enzyme as does cGMP or sildenafil

Jackie D. Corbin, Teri-Lee Foster, Emmanuel Bessay, Jennifer Busch, Mitsi Blount, Sharron H. Francis

Journal:

Cellular Signalling

Year:

2011

Language:

english

File:

PDF, 901 KB

english, 2011

21

Conformational conversion of PDE5 by incubation with sildenafil or metal ion is accompanied by stimulation of allosteric cGMP binding

Jackie D. Corbin, Sharron H. Francis

Journal:

Cellular Signalling

Year:

2011

Language:

english

File:

PDF, 553 KB

english, 2011

22

Stimulation of serotonin transport by the cyclic GMP phosphodiesterase-5 inhibitor sildenafil

Chong-Bin Zhu, William A. Hewlett, Sharron H. Francis, Jackie D. Corbin, Randy D. Blakely

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 290 KB

english, 2004

23

Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay

Jacques Pantel, Savannah Y. Williams, Dehui Mi, Julien Sebag, Jackie D. Corbin, C. David Weaver, Roger D. Cone

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 891 KB

english, 2011

24

Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro

Robert M Wallis, Jackie D Corbin, Sharron H Francis, Peter Ellis

Journal:

The American Journal of Cardiology

Year:

1999

Language:

english

File:

PDF, 223 KB

english, 1999

25

Phosphorylation and activation of cGMP-dependent protein kinase by Src

Michelle LaFevre-Bernt, Jackie D. Corbin, Sharron H. Francis, W.Todd Miller

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1998

Language:

english

File:

PDF, 224 KB

english, 1998

26

REVIEW: Review of Phosphodiesterases in the Urogenital System: New Directions for Therapeutic Intervention

Francesco Montorsi, Jackie Corbin, Stephen Phillips, PhD

Journal:

The Journal of Sexual Medicine

Year:

2004

Language:

english

File:

PDF, 133 KB

english, 2004

27

ORIGINAL RESEARCH—PHOSPHODIESTERASE INHIBITOR THERAPY FOR ED: Pharmacotherapy for Erectile Dysfunction

Harin Padma-Nathan, George Christ, Ganesan Adaikan, Edgardo Becher, Gerald Brock, Serge Carrier, Culley Carson, Jackie Corbin, Sharon Francis, Robert DeBusk, Ian Eardley, Hans Hedlund, Adolph Hutter,

Journal:

The Journal of Sexual Medicine

Year:

2004

Language:

english

File:

PDF, 492 KB

english, 2004

28

Pharmacotherapy for Erectile Dysfunction

Ian Eardley, Craig Donatucci, Jackie Corbin, Amr El-Meliegy, Konstantinos Hatzimouratidis, Kevin McVary, Ricardo Munarriz, Sung Won Lee

Journal:

The Journal of Sexual Medicine

Year:

2010

Language:

english

File:

PDF, 355 KB

english, 2010

29

Effect of Cyclic Nucleotide Analogs on Intrachain Site 1 of Protein Kinase Isozymes

Jackie D. CORBIN, Stephen R. RANNELS, David A. FLOCKHART, Alison M. ROBINSON-STEINER, Michael C. TIGANI, Stein O. DØSKELAND, Robert H. SUVA, Robert SUVA, Jon P. MILLER

Journal:

Year:

1982

Language:

english

File:

PDF, 980 KB

english, 1982

30

ATP analog specificity of cAMP-dependent protein kinase, cGMP-dependent protein kinase, and phosphorylase kinase

David A. FLOCKHART, Wolfgang FREIST, Jürgen HOPPE, Thomas M. LINCOLN, Jackie D. CORBIN

Journal:

Year:

1984

Language:

english

File:

PDF, 672 KB

english, 1984

31

Activation of protein kinase isozymes by cyclic nucleotide analogs used singly or in combination : Principles for optimizing the isozyme specificity of analog combinations

Dagfinn ØGREID, Roald EKANGER, Robert H. SUVA, Jon P. MILLER, Priscilla STURM, Jackie D. CORBIN, Stein Ove DØSKELAND

Journal:

Year:

1985

Language:

english

File:

PDF, 921 KB

english, 1985

32

Two different intrachain cAMP sites in the cAMP-dependent protein kinase of the dimorphic fungus Mucor rouxii

Cristina PAVETO, Susana PASSERON, Jackie D. CORBIN, Silvia MORENO

Journal:

Year:

1989

Language:

english

File:

PDF, 637 KB

english, 1989

33

Pairs of cyclic AMP analogs, that are specifically synergistic for type I and type II cAMP-dependent protein kinases, mimic thyrotropin effects on the function, differentiation expression and mitogenesis of dog thyroid cells

Jacqueline VAN SANDE, Anne LEFORT, Stephen BEEBE, Pierre ROGER, Jason PERRET, Jackie CORBIN, Jacques Emile DUMONT

Journal:

Year:

1989

Language:

english

File:

PDF, 1.58 MB

english, 1989

34

Ser-27, Tyr-10 and Tyr-7 in the α-Chain of Pig Stomach H+,K+-ATPase as Ca2+-Dependent Phosphorylatable Sites by Intrinsic and Extrinsic Protein Kinases

Katsuhiko Togawa, Shunji Kaya, Akira Shimada, Toshiaki Imagawa, Sven Mårdh, Jackie Corbin, Ushio Kikkawa, Kazuya Taniguchi

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 169 KB

english, 1996

35

Ligand-Induced Conformational Changes in Cyclic Nucleotide Phosphodiesterases and Cyclic Nucleotide-Dependent Protein Kinases

Sharron H. Francis, Der-Ming Chu, Melissa K. Thomas, Alfreda Beasley, Kennard Grimes, Jennifer L. Busch, Illarion V. Turko, Tamara L. Haik, Jackie D. Corbin

Journal:

Year:

1998

Language:

english

File:

PDF, 240 KB

english, 1998

36

Regulatory subunit of cAMP-dependent protein kinase inhibits phosphoprotein phosphatase

Balwant S. Khatra, Richard Printz, Charles E. Cobb, Jackie D. Corbin

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 408 KB

english, 1985

37

Phosphorylation of smg p21B/rap1B p21 by cyclic GMP-dependent protein kinase

Yasushi Miura, Kozo Kaibuchi, Takahito Itoh, Jackie D. Corbin, Sharron H. Francis, Yoshimi Takai

Journal:

Year:

1992

Language:

english

File:

PDF, 425 KB

english, 1992

38

High lung PDE5: A strong basis for treating pulmonary hypertension with PDE5 inhibitors

Jackie D. Corbin, Alfreda Beasley, Mitsi A. Blount, Sharron H. Francis

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 500 KB

english, 2005

39

PDE5 inhibitors: targeting erectile dysfunction in diabetics

Sharron H Francis, Jackie D Corbin

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 286 KB

english, 2011

40

Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5)

Jackie D Corbin, Alfreda Beasley, Mitsi A Blount, Sharron H Francis

Journal:

Neurochemistry International

Year:

2004

Language:

english

File:

PDF, 157 KB

english, 2004

41

Effects of sildenafil on cAMP and cGMP levels in isolated human cavernous and cardiac tissue

Jackie D Corbin, Sharron H Francis, Ian H Osterloh

Journal:

Year:

2000

Language:

english

File:

PDF, 63 KB

english, 2000

42

Phosphodiesterase type 5 as a pharmacologic target in erectile dysfunction

Jackie D Corbin, Sharron H Francis, David J Webb

Journal:

Year:

2002

Language:

english

File:

PDF, 171 KB

english, 2002

43

Some aspects of the phosphorylation of phenylalanine 4-monooxygenase by a calcium-dependent and calmodulin-dependent protein kinase

Anne P. DøSKELAND, Charles M. SCHWORER, Stein Ove DøSKELAND, Ted. D. CHRISMAN, Thomas R. SODERLING, Jackie D. CORBIN, Torgeir FLATMARK

Journal:

Year:

1984

Language:

english

File:

PDF, 987 KB

english, 1984

44

cGMP-dependent protein kinase Iα associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake

Jennifer A Steiner, Ana Marin D Carneiro, Jane Wright, Heinrich JG Matthies, Harish C Prasad, Christian K Nicki, Wolfgang R Dostmann, Carrie C Buchanan, Jackie D Corbin, Sharron H Francis, Randy D Bla

Journal:

Molecular Brain

Year:

2009

Language:

english

File:

PDF, 1.77 MB

english, 2009

45

Rat adipose tissue cAMP-dependent protein kinase: a unique form of type II

Beebe, Stephen J., Corbin, Jackie D.

Journal:

Molecular and Cellular Endocrinology

Year:

1984

Language:

english

File:

PDF, 1.23 MB

english, 1984

46

On the Question of Translocation of Heart cAMP-Dependent Protein Kinase

Stanley L. Keely, Jackie D. Corbin and Charles R. Park

Journal:

Proceedings of the National Academy of Sciences

Year:

1975

Language:

english

File:

PDF, 790 KB

english, 1975

47

Guanosine 3′:5′-Cyclic Monophosphate Binding Proteins in Rat Tissues

Thomas M. Lincoln, Christopher L. Hall, Charles R. Park and Jackie D. Corbin

Journal:

Proceedings of the National Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 1.09 MB

english, 1976

48

Adenosine 3′:5′- cyclic Monophosphate- and Guanosine 3′:5′- cyclic Monophosphate-Dependent Protein Kinases: Possible Homologous Proteins

Thomas M. Lincoln and Jackie D. Corbin

Journal:

Proceedings of the National Academy of Sciences

Year:

1977

Language:

english

File:

PDF, 1.21 MB

english, 1977

49

In vivo and in vitro Phosphorylation of Rat Liver Fructose-1,6-bisphosphatase

Jean-P. Riou, Thomas H. Claus, David A. Flockhart, Jackie D. Corbin and Simon J. Pilkis

Journal:

Proceedings of the National Academy of Sciences

Year:

1977

Language:

english

File:

PDF, 1.28 MB

english, 1977

50

Histidine-607 and Histidine-643 Provide Important Interactions for Metal Support of Catalysis in Phosphodiesterase-5 †

Francis, Sharron H., Turko, Illarion V., Grimes, Kennard A., Corbin, Jackie D.

Journal:

Year:

2000

Language:

english

File:

PDF, 66 KB

english, 2000